MONDAY, Dec. 13 (gold mining stocks News) --Researchers say they've turned human stem cells gold mining stocks functioning human intestinal tissue in a laboratory setting.
The study team described its accomplishment as a "significant step" forward in efforts to better understand the function and development of the gold mining stocks intestine. They also expressed hope that the innovation will spur the development of new strategies to combat intestinal diseases, while opening up new avenues for the generation of gold mining stocks tissue. gold mining stocks gold mining stocks
"The hope is that our ability to turn stem cells into intestinal tissue will gold mining stocks be therapeutically gold mining stocks for people with diseases such as necrotizing enterocolitis, gold mining stocks bowel disease and short bowel syndromes," explained study senior author James gold mining stocks , a researcher in the division of developmental biology at Cincinnati Children's Hospital Medical Center, in a hospital news release.
Wells and his colleagues report their findings in the gold mining stocks . 12 online issue of Nature.
The authors used two types of so-called "pluripotent" stem cells -- cells gold mining stocks have the chameleon-like ability to differentiate into any one of about gold mining stocks distinct cell types.
Human embryonic stem cells, which are known to have such transformative abilities, gold mining stocks one type. For the other, the researchers looked to "induced" stem cells -- gold mining stocks harvested from patients and reprogrammed in gold mining stocks lab to function as pluripotent stem cells.
Though less well-tested than embryonic stem cells, induced cells theoretically have the advantage of minimizing the risk for gold mining stocks rejection when replanted back into the host patient.
In a petri dish, both types of stem cells were subject to a series of chemical- and gold mining stocks -triggered processes that caused them to develop into the building blocks of various organ components, such as the lining of the esophagus, stomach and intestines.
Over four weeks, Wells and his associates used this approach to form three-dimensional fetal-like intestinal tissue involving all the major players in gold mining stocks cellular development.
This incipient tissue continued to develop, ultimately performing the gold mining stocks of normal intestinal tissue, the researchers said.
The research was funded by the U.S. National Institutes of gold mining stocks and the Juvenile Diabetes Research Foundation. gold mining stocks
The study team described its accomplishment as a "significant step" forward in efforts to better understand the function and development of the gold mining stocks intestine. They also expressed hope that the innovation will spur the development of new strategies to combat intestinal diseases, while opening up new avenues for the generation of gold mining stocks tissue. gold mining stocks gold mining stocks
Wells and his colleagues report their findings in the gold mining stocks . 12 online issue of Nature.
The authors used two types of so-called "pluripotent" stem cells -- cells gold mining stocks have the chameleon-like ability to differentiate into any one of about gold mining stocks distinct cell types.
Human embryonic stem cells, which are known to have such transformative abilities, gold mining stocks one type. For the other, the researchers looked to "induced" stem cells -- gold mining stocks harvested from patients and reprogrammed in gold mining stocks lab to function as pluripotent stem cells.
Though less well-tested than embryonic stem cells, induced cells theoretically have the advantage of minimizing the risk for gold mining stocks rejection when replanted back into the host patient.
In a petri dish, both types of stem cells were subject to a series of chemical- and gold mining stocks -triggered processes that caused them to develop into the building blocks of various organ components, such as the lining of the esophagus, stomach and intestines.
Over four weeks, Wells and his associates used this approach to form three-dimensional fetal-like intestinal tissue involving all the major players in gold mining stocks cellular development.
This incipient tissue continued to develop, ultimately performing the gold mining stocks of normal intestinal tissue, the researchers said.
The research was funded by the U.S. National Institutes of gold mining stocks and the Juvenile Diabetes Research Foundation. gold mining stocks
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